前列腺增生体积、症状积分和梗阻程度的相关性研究

Correlation among international prostatic symptom score,prostate volume and bladder outlet obstruction in men with BPH

目的:探讨前列腺增生体积、症状积分和膀胱出口梗阻程度的相关性。方法:对43例住院手术的前列腺增生症患者进行国际前列腺症状评分(IPSS),其中经腹壁B超测前列腺体积(V)者27例;行排尿期尿道测压确定膀胱出口梗阻者27例,并用压力下降梯度(MUPPGradient)代表梗阻程度。结果:IPSS和V呈正相关(n=27,r=0.3933,P=0.021),IPSS和MUPPGradient呈正相关(n=27,r=0.5120,P=0.003),V和MUPPGradient呈正相关(n=20,r=0.5077,P=0.011)。结论:症状积分、前列腺体积和膀胱出口梗阻程度有一定的相关性,可作为临床上手术切除增生前列腺组织,解除梗阻。

Purpose:In an attempt to increase our understanding of the clinical syndrome of benign prostatic hyperplasia (BPH), an analysis was made of the relationships among symptoms, prostate volume and severity of bladder outlet obstruction (BOO).Methods:Symptoms were assessed with international prostatic symptom score (IPSS) in 43 cases. Prostate volume was estimated by transabdominal ultrasonography in 27 cases, and BOO was measured by micturitional urethral pressure profilometry (MUPP) in 27 cases. The severity of obstruction was determined by the magnitude of the micturitional urethral pressure profile gradient.Results:There was significant correlation between symptoms and prostate volume(r= 0.3933 ,P= 0.021 ),between symptoms and severity of BOO(r= 0.5120 ,P= 0.003 ),between prostate volume and severity of BOO(r= 0.5077 ,P= 0.011 ).Conclusions:These results suggested a somewhat stronger, albeit modest relationships among symptoms, prostate volume and severity of BOO.