马脾铁蛋白释放铁的反应级数和速率相数的转换

TRANSFER OF REACTION ORDERS AND PHASE NUMBERS OF IRON RELEASE RATE OF HORSE SPLEEN FERRITIN

采用差示法研究铁蛋白释放铁的动力学规律和反应级数的转换。结果表明：马脾铁蛋白释放铁的速率及相数与还原剂Na2S2O4。浓度及铁还原速率无关，与该蛋白蛋白壳的调节速率有关。在pH50～6．0范围内，马脾铁蛋白以三相不同速率方式释放占原铁核总铁量80％的铁。但在pH9．0介质中，OH-不仅能参与铁蛋白铁核组成，减缓释放铁的速率，而且使原混合级反应转换为一级反应，从而使铁蛋白释放铁的动力学过程由复杂转化为简单。

A differential technique was used to study kinetics about the law of iron release as well as the transfer of reaction order of horse spleen ferritin. The rate of iron release and the phasic numbers from ferritin are independent of the reducer (Na2S2O4) concentration and the rate of iron reduction, but related to the regulation rate of the protein shell. Ferritin released 80% of its original iron content at different rates of three phases between pH 5. 0 and 6.0. However, at pH 9. 0 of the medium, OH- ions not only took part in the composition of the iron core and retard the rate of iron release from the ferritin, but also caused the rate of reaction turn from mix-orders to first-order, thus transferring the complicated process of kinetics of iron release into a simple form.