海南省琼中地区三农场斑点热血清流行病学研究

Study on Seroepidemiological Investigation of Spotted Fever in Qiongzhong Area of Hainan Province

目的：了解海南省斑点热流行状况。方法：用补体结合试验，在琼中县大丰、阳江及新进３个农场的健康人群、家畜及啮齿动物中进行斑点热血清流行病学及啮齿动物种群和带蜱情况调查。结果：共检查牛血清１８份，羊血清５０份，猪血清６３份，人血清７２份，鼠血清１２０份，西伯利亚立克次体、康氏立克次体、小蛛立克次体抗体阳性率羊血清分别为４％（２／５０）、２％（１／５０）和２％（１／５０）。猪血清分别为３．１７％（２／６３）、０％（０／６３）和３．１７％（２／６３），人血清分别为１６．６７％（１２／７２）、１１．１１％（８／７２）和２．７８％（２／７２），鼠血清分别为３０．００％（３６／１２０）、１０．８３％（１３／１２０）和７．５０％（９／１２０），牛血清中未检测出上述抗体。该地区的优势鼠种为黄毛鼠、屋顶鼠、针毛鼠，带蜱率分别为１５．９１％（７／４４）、３０％（１５／５０）、３６．３６％（８／２２）。结论：海南省琼中县存在斑点热自然疫源地。

In order to understand an epidemic situation of spotted fever in Hainan province, serosurvey and kinds of rodent and their tick-carriing investigation were carried out by using CF in Dafeng、Yangjiang and Xinjin counties in Hannan province.The results showed that prevalence of antibodies to R.sibirica,R.conorii and R.akari were 4% (2/50)、2%(1/50)and 2%(1/50) respectively in sheep; 3.17%(2/63)、0%(0/63)and 3.17%(2/63),respectively in pig;16.67%(12/72)、11.11%(8/72) and 2.78%(2/72),respectively among healthy persons; and 30%(36/120)、10.83%(13/120) and 7.50%(9/120) respectively in wild rats;there was no antibody to spotted fever group rickettsiae to be found in cattle serum.The major wild rats were R.losea,R.rattus hainanieus and R.fulvescens ,the tick-bearing rate were respectively 11.91%(7/44)、30.00%(15/50)and 36.36 %(8/22). The results suggested that there exsit natural foci of spotted fever in Qiongzhong area of Hainan province.