高效的骨诱导生长因子——成骨蛋白-1

High Efficient Bone Inductive Factor Osteogenic Protein 1.

成骨蛋白１（ＯＰ１）又称骨形态发生蛋白７（ＢＭＰ７），属转化生长因子β（ＴＧＦβ）超家族成员．重组人ＯＰ１（ｒｈＯＰ１）在体内和体外都显示了高效的骨诱导活性，可使多种实验动物的骨缺损满意愈合。

Osteogenic protein 1(OP 1, or bone morphogenetic protein 7) is a member of the transforming growth factor(TGF) β superfamily. It has been testified that recombinant human OP 1(hOP 1) indicated potent bone inductive efficiency in vitro and in vivo . The satisfactory results were obtained from healing bone defects in many kinds of experimental animals with hOP 1.Recombinant hOP 1 has prospective clinical application.