不同视觉经验中zif268基因的表达模式

Expression Patterns of zif268 Induced by Different Visual Experiences.

ｉｆ２６８基因编码一转录因子ＺＩＦ２６８．在发育的视皮层中，ｚｉｆ２６８基因的表达模式受发育的调节．在具有正常视觉经验的视皮层中，ｚｉｆ２６８基因有较高水平的表达．视觉废置后，视皮层内该基因的表达水平显著降低．通过视觉刺激可显著增强该基因的表达．

The gene zif 268 codes for a transcription factor ZIF268. The expression pattern of zif 268 in developing visual cortex is regulated. zif 268 is highly expressed in adult visual cortex which experienced normal visual input. After visual deprivation, the expression level of zif 268 is strongly down regulated , while visual stimulation can significantly increase the expression level of zif 268. The studies concerning the expression pattern of zif 268 offer further insight into the physiological functions of zif 268 in the mammalian visual system.