盐酸氟哌噻吨美西辛辅助治疗肠易激综合征66例疗效分析

The curative effect of deanxit in adjuvant treatment of 66 patients with irritable bowel syndrome

目的 探讨盐酸氟哌噻吨美西辛（黛力新）辅助治疗对肠易激综合征患者心理和临床疗效的作用.方法 回顾性分析66例肠易激综合征患者的临床资料,对照组按常规治疗,观察组在治疗组的基础上给于黛力新辅助治疗,观察两组疗效.结果 132例患者中,确诊存在焦虑的患者98例,抑郁患者9例,发病率为81%;观察组治疗前后SAS、SDS评分差异有统计学意义（均P＜0.05）,对照组治疗前后SAS、SDS评分差异无统计学意义（均P＞0.05）;与对照组相比,观察组治疗显效率和总有效率均明显升高（均P＜0.05）.结论 黛力新辅助治疗肠易激综合征能显著改善患者焦虑/抑郁水平,提高临床疗效.

Objective To investigate the effect of deanxit in adjuvant treatment of the patients with irritable bowel syndrome and the psychologicalon of the patients. Methods Clinical data of 66 patients with irritable bowel syndrome were retrospectively analyzed. The control group was treated by conventional therapy, and the observation group was given deanxit based on the treatment of the control group. Then the curative effect were observed. Results In 132 patients,98 cases were troubed with anxiety,9 cases with athymia, the incidence rate was 81%. After treatment the SAS and SDS score of the observation group reduced,compared with before treatment,and the difference was significant（ P ＜0. 05 ）; Before and after treatment the SAS and SDS score of the control group had no significant difference（P ＞0. 05）. Compared with the control group,the excellence and total effective rate increased significantly in the observation group（P ＞ 0. 05）. Conclusion Adjunctive therapy with deanxit could improve the anxiety and athymia,and elevate clinical curative effect.