《中国药典》中哈蟆油的基原问题诹议

On origin of Oviductus Ranae in Chinese Pharmacopoeia

目的:根据历史文献、近代国内外学者及作者的研究,诹议《中国药典》中哈蟆油的基原问题。方法:综合分析文献资料报道,从史书记载、形态学、染色体组型、银带及同工酶电泳、基因水平等方面,探讨哈蟆油的原动物基原。结果与结论:名贵药材哈蟆油的原动物基原应为东北林蛙Rana dybowskii,其分类阶元为我国蛙类的一有效物种,建议《中国药典》应将哈蟆油的原动物确定为东北林蛙,以避免哈蟆油原动物名称混乱问题。

Objective： To discuss the problem about the origin of Oviduetus Ranae in the Chinese Pharmacopoeia according to historical documents,the researches reported recently and the author research.Method： Through comprehensive analysis of the documents and materials reported,the original animal sources of Oviduetus Ranae was discussed in terms of historical records,morphology,karyotype,Ag-Belt and isoenzyme electrophoresis,gene levels and so on.Result and Conclusion： The original animal sources of Oviduetus Ranae is Rana dybowskii,its order element is an effective species in China.In order to avoid the problem of species confusion about the origin of Oviduetus Ranae,author suggests that R.dybowskii should be the original animal of Oviduetus Ranae.