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A DLM/FD/IB Method for Simulating Cell/Cell and Cell/Particle Interaction in Microchannels 被引量:2

A DLM/FD/IB Method for Simulating Cell/Cell and Cell/Particle Interaction in Microchannels
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摘要 A spring model is used to simulate the skeleton structure of the red blood cell (RBC) membrane and to study the red blood cell (RBC) rheology in Poiseuille flow with an immersed boundary method. The lateral migration properties of many cells in Poiseuille flow have been investigated. The authors also combine the above methodology with a distributed Lagrange multiplier/fictitious domain method to simulate the interaction of cells and neutrally buoyant particles in a microchannel for studying the margination of particles. A spring model is used to simulate the skeleton structure of the red blood cell (RBC) membrane and to study the red blood cell (RBC) rheology in Poiseuille flow with an immersed boundary method. The lateral migration properties of many cells in Poiseuille flow have been investigated. The authors also combine the above methodology with a distributed Lagrange multiplier/fictitious domain method to simulate the interaction of cells and neutrally buoyant particles in a microchannel for studying the margination of particles.
出处 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2010年第6期975-990,共16页 数学年刊(B辑英文版)
基金 supported by the National Science Foundation of the United States (Nos. ECS-9527123, CTS-9873236, DMS-9973318, CCR-9902035, DMS-0209066, DMS-0443826, DMS-0914788)
关键词 粒子相互作用 通道细胞 POISEUILLE流 模拟 DLM 拉格朗日乘子 红血细胞 骨架结构 Red blood cells Elastic spring model Margination Fictitious domain method Immersed boundary method Microchannel
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参考文献38

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