视网膜色素上皮细胞的诱导分化及其移植治疗方法的研究进展
摘要
视网膜色素上皮(retinal pigment epithelium,RPE)的病变可以导致多种视网膜疾病,目前缺乏有效的治疗手段。人类多能干细胞具有多向分化潜能,为此类疾病的细胞治疗提供了理想来源。本文将近年来胚胎干细胞和诱导多能干细胞体外定向分化为RPE细胞及移植治疗年龄相关性黄斑变性等视网膜疾病的研究进行了综述。
出处
《国际眼科纵览》
2010年第5期329-333,共5页
International Review of Ophthalmology
基金
国家重点基础研究发展计划(973计划)(2011CB965102)
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