体质量指数对病情分级相同的阻塞性睡眠呼吸暂停低通气综合征患者的影响

Influence of BMI to the patients with obstructive sleep apnea-hypopnea syndrome in the same grade

目的 探讨体质量指数（BMI）对病情分级相同的阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea-hypopnea syndrome,OSAHS）患者的影响.方法 选取267例已行多导睡眠监测的OSAHS患者,按国内通用BMI标准分两组,BMI≥24者为肥胖组（206例）,BMI＜24者为正常组（61名）.按AHI及夜间最低SaO2将患者病情分为轻、中、重三级,分别比较相同病情分级的正常与肥胖两组患者睡眠结构、呼吸紊乱、临床症状及合并症的情况.结果 病情分级相同的OSAHS患者因BMI不同,睡眠结构、呼吸紊乱程度及合并症差异有统计学意义（P＜0.05）,肥胖组病情严重程度重于正常组,合并症比例高于正常组,在重度分级中差异显著.结论 肥胖使OSAHS患者的病情严重程度加重,随着OSAHS病情分级的加重,肥胖对于OSAHS的影响也更加明显.

Objective To investigation the influence of body mass index （BMI） to the patients with obstructive sleep apnea-hypopnea syndrome （OSAHS） in the same grade. Methods 267 patients with OSAHS were examined by PSG. According to BMI,divide the patients into normal group（BMI〈24） and fat group （BMI≥ 24）. According to AHI and arterial oxygen saturation, divide the patients into light grade, moderate grade, severe grade, and compare the sleep structure, breathing disorder, clinical symptoms, complications between the normal group and the fat group in the same grade. Results Sleep structure, breathing disorder,clinical symptoms,complications of patients with OSAHS in the same grade were significantly different among those with different BMI（ P 〈0. 05）, the fat group are more severe.Conclusions Obesity increases the severity of OSAHS, and with the grade of OSAHS increasing, the influence of obesity to OSAHS is more obvious.