射频消融在直肠癌术后盆腔复发的临床探讨

Evaluation of Radiofrequency Ablation in the Treatment of Pelivic Recurrence in Rectal Cancer

目的本研究主要是评估射频消融在直肠癌术后盆腔复发的有效性。方法 6位直肠癌术后复发的患者,术前评估肿瘤不能切除,予放化疗和止痛药治疗后,仍伴有顽固剧烈疼痛,在CT定位指引下,予射频消融治疗。结果治疗过程没有大的并发症。5例患者埋怨盆腔有灼热感但可以忍受。治疗后复查MR示肿瘤明显坏死,疼痛明显减轻,服用止痛药明显减少。血清CEA明显下降。6个月后复查肿瘤无明显复发。结论射频消融治疗直肠癌术后盆腔复发,操作相对简单安全,值得临床上进一步积累经验。

Objective The aim of this study was to asses the efficacy of radiofrequency ablation in the treatment of pelvic recurrent rectal cancer.Methods Computed tomography guided percutaneous radiofrequency ablation was performed by placing a LeVeen needle electrode into the tumor.Radio frequency abation was performed on 7 lesion in 6 patients with pelvic recurrent rectal cancer,where the tumors were unresectal associatted with poorly controllable pain despite local treatment consisting chemoradiotherapy.Results There were no major complications during the radiofrequency ablation proce dure,although 5 patient complained of a sensation of warmth in the pelvic region,which was reasonably tolerated.Post radiofrequency ablation imaging showed viable tissue remmant in tumor mangin,but the treatment produced relief of pain.The procedure was effective in opioid dosage reduction and pain control within a limited time span.Conclusion Radiofrequency ablation is a reclative readily maneuverable and safe local treatment for pelvic recurrence in rectal cancer and is considered a procedure worth applying with further accumulation of experience in clinical cases.