摘要
用苯基格氏试剂与硼酸三正丁酯在室温下反应制得苯基硼酸，以苯基硼酸与对二溴苯为原料，以氯化钯为催化剂，以四丁基碘化铵为相转移催化剂及在碳酸钾的参与下，在水／苯为介质的非均相体系中进行偶联反应，合成了对三联苯，产率达７０％（以对二溴苯计）。物料摩尔配比为：对二溴苯∶苯基硼酸∶氯化钯∶四丁基碘化铵∶碳酸钾＝１∶２．２∶０．０１∶１∶５。
p Terphenyl has been synthesized by the ligandless palladium chloride catalyzed crosscoupling reaction of phenyl boronic acid with 1,4dibromobenzene (molar ratio 2.21) in water/benzene in the presence of tetrabutylammonium iodide in 70% yield.The phenyl boronic acid was prepared in 43% yield by the reaction of phenylmagnesium bromide with tributyl borate at room temperature.\=
出处
《精细化工》
EI
CAS
CSCD
北大核心
1999年第3期17-19,共3页
Fine Chemicals
基金
国家自然科学基金
关键词
氯化钯
交叉偶联
三联苯
催化
联苯
palladium chloride
crosscoupling
p terphenyl\= Foundation item: Granted by the natural science funds of China(29574169)
