模拟酶催化剂催化氧气液相氧化对硝基甲苯邻磺酸的研究 Ⅰ.催化剂对反应的影响

Oxygen Oxidation of p Nitrotoluene o sulfonic Acid with \= Simulated Enzyme Catalyst\= Effect of Catalyst on Reaction

研究了催化剂种类及用量对氧气液相氧化对硝基甲苯邻磺酸（ＮＴＳ）制取４，４’二硝基二苯乙烯２，２’二磺酸（ＤＮＳ）的影响。发现在水介质中以价廉易得的模拟酶催化剂，在其最佳用量ｗ（底物）＝１％、ｃ（ＮａＯＨ）＝１．０ｍｏｌ／Ｌ、ｃ（ＮＴＳ）＝０．３８ｍｏｌ／Ｌ时，６０℃下反应１８ｈ，可以获得８１．８％的粗品收率，其纯度可达９６．７％。ＤＮＳ的结构通过核磁共振谱得以确认。

The effect of catalyst and its consumption on preparation of 4,4'dinitrostilbene2,2'disulfonic acid by means of oxygen oxidation of p nitrotoluene o sulfonic acid in liquidphase were investigated.The results showed that oxygen liquidphase oxidation of p nitrotoluene o sulfonic acid by choosing simulated enzyme as catalysts with 1% NTS( m/m ), c (NaOH)=1mol/L, and c (NTS)=0.38mol/L in water solution at 60 for 18h could give 4,4'dinitrostilbene2,2'disulfonic acid in 81.8% yield and in 96.7% purity which was determined with HPLC.The structure of DNS was confirmed by \+1 HNMR.\=