摘要
多糖基分子印迹功能材料因原料来源广泛、生物相容性和生物降解性好等优点,近年来引起国内外广泛关注。本文综述了利用环糊精、壳聚糖、纤维素、海藻酸、琼脂、淀粉等天然多糖制备分子印迹功能材料的主要方法,包括直接交联法、接枝共聚交联法和溶胶-凝胶技术,评述了其在分离、生物传感、药物传输、蛋白质复性等方面的应用,并对其未来的发展进行了展望。
In recent years,molecularly imprinted materials （MIMs） based on polysaccharides have attracted great attention due to their abundant raw materials,good biodegradability and biocompatibility.In this paper,the preparation methods of MIMs based on natural polysaccharides such as cyclodextrin,chitosan,cellulose,alginic acid,agarose and starch are reviewed,including direct crosslinking,graft-copolymerization crosslinking and sol-gel technique.Their applications in separation,solid phase extraction,biosensing,drug delivery and protein refolding are discussed.In addition,the development trend of polysaccharide-based MIMs is prospected.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2010年第11期2165-2172,共8页
Progress in Chemistry
基金
国家自然科学基金项目(No.20874116
20676155)
教育部高等学校博士点基金项目(No.20090171110023)资助
关键词
多糖
分子印迹
功能材料
polysaccharides
molecularly imprinting
functional materials
