无症状女性人群及宫颈炎患者泌尿生殖道标本的沙眼衣原体MOMP基因分布

Distribution of Genotype of Chlamydia Trachomatis from the Cervical Swabs of the Cervicitis and Asymptomatic Women.

目的了解广东省部分地区沙眼衣原体泌尿生殖道感染者的基因型分布特点。方法运用扩增沙眼衣原体外膜蛋白（ＭＯＭＰ）基因限制性内切酶片段长度多态性（ＲＦＬＰ）方法对无症状女性及宫颈炎患者泌尿生殖道标本进行了基因分型检测。结果基因Ｅ型在两组人群中分布最高，宫颈炎患者以Ｆ、Ｇ二型多见，无症状组以Ｄ型多见。结论实验结果对进一步分析常见的沙眼衣原体慢性迁延感染机理提供了实验依据。

Objective To investigate the Chlamydia trachomatis genotype distribution in asymptomatic women and cervicitis patients in some areas of Guangdong Province.Method Genotype of the major outer membrane proteins (MOMP) were classified in asymptomatic women and cervicitis patinets,by using restriction enzymes assay(RELP).Result Genotype E was predominat in both the patients and asymptomatis women.Genotype F and G were more commonly found in Cervicitis women.Genotype D was more commonly found in asymptomatics women.Conclusion The result may lay the fundation of the mechanism of the prolonged infection of Chlamydia trachomatis.