应用糖皮质激素治疗巨大肥厚性胃炎1例

Giant hypertrophy gastritis responses to glucocorticoid:a case report

目的探讨巨大肥厚性胃炎的临床特点和诊治方法。方法报道1例以低蛋白血症为主要临床表现的巨大肥厚性胃炎,通过影像学、内镜检查及病理组织学明确诊断,并给予糖皮质激素治疗。结合文献复习,探讨其病理、临床、诊断及治疗特点。结果内镜下见胃体黏膜皱襞增厚,超声内镜示胃底、胃体黏膜层显著增厚,病理诊断符合肥厚性胃炎。予以激素治疗后患者血白蛋白恢复正常。结论激素治疗巨大肥厚性胃炎有效,应加深对其诊治的认识和了解。

Objective To investigate the clinical feature,diagnosis and therapy of giant hypertrophy gastritis.Methods We reported a case of giant hypertrophy gastritis with hypoproteinemia secondary to a loss of albumin into the gastric lumen.The diagnosis of giant hypertrophy gastritis was made by a combination of radiologic examination,endoscopic imaging,and histologic analysis.Glucocorticoid treatment was applied to the patient.Through literature review,the clinical and pathological features,diagnosis,therapy of giant hypertrophy gastritis were reviewed.Results Endoscopic and radiologic examination revealed enlarged gastric folds on the body of stomach.Endoscopic sonography revealed marked thickening of mucosal layer on the body of stomach and gastric fundus.Pathologic findings are consistent with giant hypertrophy gastritis.After glucocorticoid treatment,hypoproteinemia resolved.Conclusion Giant hypertrophy gastritis may response to glucocorticoid.