摘要
在０．１２ｍｏｌ·Ｌ－１ＫＣｌ溶液中，西咪替丁在单扫示波极谱上有一灵敏的导数极谐波，峰电位Ｅｐ＝１．０９Ｖ（ｖｓ·ＳＣＥ）·峰电流ｉｐ与西咪替丁浓度在１．０Ｘ１０－６～１５Ｘ１０－５ｍｏｌ·Ｌ－１范围内成线性关系．检出限为５．０ｘ１０－７ｍｏｌ·Ｌ－１．并用于片剂的测定，得到满意的结果．用线性扫描和循环伏安法探讨体系的伏安吸附行为．结果表明，该体系属于具有吸附性的不可逆过程．
In 0.12nik.L-1 KCl solution,a well reduction peak of cimetidine is obtained by single-sweep oscillopolarography.The peak potential is-1.09V(vs.SCE).The peak cur-.rent is proportional to the concentration of cimetidine over the range of 1.0 10-6~1.510-5molL-1.The detection limit is5.010-7mol.L-1.The method is applied to the determinationof cimetidine in tablet with satisfactory results.The voltammetric and adsorptive behavior ofthe system is studied by means of linear sweep and cyclic voltammetry.The wave is a quasi-reversible wave with adsorptive property.
出处
《北京师范大学学报（自然科学版）》
CAS
CSCD
北大核心
1999年第1期83-86,共4页
Journal of Beijing Normal University(Natural Science)
基金
国家自然科学基金
宁夏自治区科委基金
关键词
西咪替丁
伏安行为
吸附行为
单扫示波极谱法
cimetidine
voltammetric behavior
adsorptive behavior
single-sweep oscillo-polarography
