法莫替丁联合维生素K1治疗新生儿消化道出血疗效观察

The effects of famotidine combined with vitamin K1 on the therapy of neonatal alimentary tract hemorrhage

目的 观察法莫替丁联合维生素K1对新生儿消化道出血的治疗效果.方法 69例患儿随机分为对照组（24例,常规治疗加维生素K1组）,治疗组（45例,对照组治疗方法基础上联用法莫替丁组）.观察出血停止时间,对疗效进行评价.结果 治疗组显效率77.8%,总有效率95.6%,显著高于对照组的显效率45.8%和总有效率70.8%（P＜0.05）.结论 法莫替丁联合维生素K1治疗新生儿消化道出血可更好的提高新生儿消化道出血的治疗效果,是安全有效的治疗方法.

Objective To observe the therapeutic efficacy of famotidine combined with vitamin K1 on neonatal alimentary tract hemorrhage. Methods 69 neonates with neonatal alimentary tract hemorrhage were divided into control group （24 neonates who accepted the conventional therapy combined with vitamin K,） and therapy group （45 neonates who got the treatment of control group combined with famotidine）. The effects were evaluated by the offtime of hemorrhage. Results The total curative effect of the therapy group was 95.6% .which significantly higher than that in control group（70. 8% ） ,P 〈 0.05. Conclusion Famotidine combined with vitamine K1 could improve the therapeutic efficacy of the treatment of neonatal alimentary tract hemorrhage. It was a safe and effective method in the treatment of neonatal alimentary tract hemorrhage.