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子宫内膜异位症患者血清IL-6、IL-8与TNF-α的水平变化 被引量:3

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摘要 目的 探讨子宫内膜异位症(EMS)患者血清白细胞介索6(IL-6)、白细胞介素8(IL-8)、肿瘤坏死因子α(TNF-α)的水平变化及临床意义.方法 应用酶联免疫吸附法(ELISA)测定50例EMS患者(Ⅰ~Ⅱ期22例、Ⅲ~Ⅳ期28例)手术前后血清IL-6、IL-8与TNF-α的水平,并与35例非子宫内膜异位症(对照组)患者作比较.结果 EMS组患者血清IL-6、IL-8与TNF-α的水平均高于对照组(P<0.05);EMS组Ⅲ~Ⅳ期患者血清中IL-6、IL-8与TNF-α水平高于Ⅰ~Ⅱ期患者(P<0.05);手术后其水平下降,与术前比较差异有统计学意义(P<0.05),术后与对照组比较差异无统计学意义(P>0.05).结论 EMS患者血清中IL-6、IL-8与TNF-α水平明显增高,它们与EMS的发生发展密切相关,检测EM患者IL-6、IL-8与TNF-α水平对病情和预后判断均有重要的临床意义.
作者 商彩霞
出处 《中国基层医药》 CAS 2010年第13期1801-1802,共2页 Chinese Journal of Primary Medicine and Pharmacy
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