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内镜下植入缓释化疗粒子治疗食管、胃癌的近期疗效观察 被引量:3

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摘要 目的观察内镜下植入缓释化疗粒子5-氟尿嘧啶(5-Fu)治疗食管、胃癌患者的近期疗效。方法选择14例进展期隆起型食管、胃癌患者,内镜直视下对癌灶植入缓释化疗粒子5-Fu(每粒含5-Fu1.67 mg)55~63粒,平均注射粒子100 mg,治疗后第2周、第4周评价其缓解疼痛等临床疗效及毒副作用。结果 14例患者显著有效4例,明显有效4例,有效3例,无效3例,总有效率79%;无一例患者发生严重出血和穿孔等并发症;肝、肾功能及血常规检查未见异常。结论内镜直视下植入缓释化疗粒子5-Fu治疗食管、胃癌近期疗效显著,且无明显毒副作用,值得临床进一步推广。
出处 《现代中西医结合杂志》 CAS 2010年第33期4284-4285,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
基金 南京市江宁区科技局资助项目(2007-003)
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