莲须化学成分的研究

Studies on Chemical Constituents of Stamen Nelumbinis

目的研究莲须的化学成分。方法应用溶剂法进行提取,采用硅胶柱色谱和聚酰胺柱色谱方法分离和纯化化合物,通过理化性质和波谱数据鉴定化合物结构。结果从体积分数95%乙醇提取物中分离并鉴定了16个化合物,分别为1-癸醇(Ⅰ)、二十四烷酸(Ⅱ)、棕榈酸(Ⅲ)、环阿尔廷醇(Ⅳ)、环阿尔屯烷-23-烯-3,β25-二醇(Ⅴ)、金色酰胺醇酯(Ⅵ)、β-谷甾醇(Ⅶ)、胡萝卜苷(Ⅷ)、棕榈酸-α,α′-甘油二酯(Ⅸ)、二十六烷酸-α-甘油酯(Ⅹ)、对苯二酚(Ⅺ)、对羟基苯甲酸(Ⅻ)、丁二酸(X)、山柰酚(X)、山柰酚-3-O-β-D-吡喃半乳糖苷(ⅩⅤ)、异鼠李素(ⅩⅥ)。结论化合物Ⅰ、Ⅳ～Ⅵ、Ⅸ～Ⅻ为首次从该植物中分离得到,化合物Ⅱ、Ⅲ、Ⅶ、Ⅷ为首次从莲须中分离得到。

OBJECTIVE To study the chemical constituents of Stamen Nelumbinis.METHODS The chemical constituents were isolated by silica gel chromatography and polyamide column chromatography.And their structures were elucidated by physical-chemical and spectroscopic methods.RESULTS Sixteen compounds were isolated and their structures were identified as decadal alcohol（Ⅰ）,tetracosanoic acid（Ⅱ）,palmitic acid（Ⅲ）,cycloartenol（Ⅳ）,cycloart-23-en-3β,25-diol（Ⅴ）,aurantiamide acetate（Ⅵ）,β-sitosterol（Ⅶ）,daucosterol（Ⅷ）,hexadecanoic acid-2-hydroxy-1,3-propanediyl ester（Ⅸ）,hexacosanoic acid 2,3-dihydroxypropyl ester（Ⅹ）,hydroquinone（Ⅺ）,p-hydroxybenzoic acid（Ⅻ）,succinic acid（）,kaempeferol（）,kaempferol-3-O-β-D-galactopyranoside（ⅩⅤ） and isorhamnetin（ⅩⅥ）.CONCLUSION Compounds Ⅰ,Ⅳ-Ⅵ,Ⅸ-Ⅻ are isolated from this plant for the first time,and compound Ⅱ,Ⅲ,Ⅶ and  are isolated from Stamen Nelumbinis for the first time.