摘要
目的研究我国瑶族植物药扁担藤[Tetrastigma planicaule(Hook.)Gagnep.]的化学成分。方法采用色谱技术进行分离,根据化合物的理化性质和光谱数据鉴定其结构。结果从扁担藤茎的体积分数95%乙醇提取物中分离得到8个化合物,分别鉴定为stigmast-4-en-6β-ol-3-one(1),7α-hydroxysitosterol(2),古柯二醇(3),水杨酸(4),香草酸(5),丁香酸(6),原儿茶酸(7),glycerol-2-(3-methoxy-4-hydroxybenzoic acid)ether(8)。结论所有化合物均为首次从该植物中分离得到,其中化合物1~3,5~8为首次从该属植物中分得。化合物8为首次从天然产物中分离得到。
OBJECTIVE To investigate the chemical constituents of Tetrastigma planicaule(Hook.) Gagnep as a medicinal plant of Yao nationality in China.METHODS Compounds were isolated by various column chromatography.Their structures were elucidated by physicochemical and spectral analysis.RESULTS Ten compounds were isolated from the 95% ethanol extract of the stems of Tetrastigma planicaule and their structures were identified as stigmast-4-en-6β-ol-3-one(1),7α-hydroxysitosterol(2),erythrodiol(3),salicylic acid(4),vanillic acid(5),syringic acid(6),protocatechuic acid(7) and glycerol-2-(3-methoxy-4-hydroxybenzoic acid) ether(8) respectively.CONCLUSION All these compounds were isolated from this plant for the first time,and compound 1-3,5-8 were firstly isolated from the genus Tetrastigma.Compound 10 was isolated from natural products for the first time.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2010年第21期1615-1617,共3页
Chinese Pharmaceutical Journal
基金
国家自然科学基金资助项目(20472024
20772047)
广东省自然科学基金资助项目(039213)
关键词
扁担藤
化学成分
酚酸
Tetrastigma planicaule
chemical constituents
phenolic acid