我院282例药品不良反应报告分析

Retrospective Analysis of 282 Case Reports of Adverse Drug Reactions in Our Hospital

目的:了解我院药品不良反应(ADR)发生的特点及规律。方法:对我院2008～2009年收集的282例ADR报告进行分类统计与分析。结果:282例ADR中,男性(162例)多于女性(120例),>60岁者占34.04%;抗微生物药引起的ADR最为多见,占44.68%,其次为消化系统药,占13.12%;静脉滴注较其他给药途径更易发生ADR(240例,占85.11%);主要的ADR类型为皮肤及其附件损害,占44.33%。结论:临床应加强和重视ADR的监测工作,促进合理用药。

OBJECTIVE：To investigate the characteristics and regularity of adverse drug reactions（ADR）occurred in our hospital. METHODS：A total of 282 cases of ADR reports collected in our hospital in 2008～2009 were classified and analyzed statisti- cally. RESULTS：Among the 282 cases,the male（162 cases）showed higher proportion than female（120 cases）,and senile patients who were more than 60 years accounted for 34.04%. The antimicrobial drugs caused 44.68% of ADR,followed by the digestive system medicines（13.12%）. The ADR were more likely caused by intravenous injection（240 cases,85.11%）. Main types of ADR were lesions of skin and its appendents,accounting for 44.33%. CONCLUSION：Great importance should be attached to ADR monitoring to promote rational drug use in the clinic.