我院252例药疹住院病例报告分析

Analysis of 252 Inpatients with Drug Eruptions in Our Hospital

目的:探讨临床用药与药疹发生的关系及临床表现。方法:对我院2008～2009年药疹住院病例进行回顾性分析。结果:252例患者中,最常见致敏药物为抗感染药(占46.06%),其次为非甾体类抗炎药(占19.68%)、中药制剂(占15.51%)。药疹类型以皮疹型居首位(占38.10%),其次是多形红斑型(占16.67%)、荨麻疹型(占13.10%)。结论:临床应合理、规范用药,杜绝药物滥用。

OBJECTIVE：To analyze the relationship of drug eruption with clinical use of drug and clinical manifestation of drug eruption. METHODS：Hospitalized cases of drug eruption in our hospital from 2008 to 2009 were analyzed retrospectively. RESULTS：Of total 252 cases,46.06% of allergy-inducing drug were anti-infective agents,followed by NSAID（19.68%）and traditional Chinese medicines preparation（15.51%）. The most common type of drug eruptions was erythra（38.10%）,followed by erythema polymorphe（16.67%）and urticaria（13.10%）. CONCLUSION：Great importance should be attached to rational standardized use of drugs to avoid drug abuse.