摘要
目的:评价萘哌地尔治疗输尿管下段结石的临床效果。方法:将120例输尿管下段结石患者随机分为实验组和对照组,每组60例。两组患者均口服氧氟沙星0.4g/d,中成药尿石通丸12g/d,实验组加服萘哌地尔50mg/d,观察随访3周。结果:实验组和对照组结石完全排出率分别为91.7%(55/60)和53.3%(32/60),有效实验组为57例,对照组为38例,两组比较,差异有统计学意义(P<0.05);实验组排石时间、肾绞痛发生次数明显少于对照组,差异有统计学意义(P<0.05);两组未发现明显药物副作用。结论:萘哌地尔能有效促进输尿管下段结石排出,缩短排石时间,并减少排石过程中肾绞痛的发生。
Objective：To evaluate the clinical effects of naftopidil on patients with lower ureteral stones.Methods：120 patients with lower ureteral stones were randomly divided into 2 groups,60 cases in each group.Both groups accepted ofloxacin 0.4 g/d and the traditional Chinese medicine niaoshitong 12 g/d.The experimental group accepted naftopidil 50 mg/d.All patients were followed up for 3 weeks.Results：The expulsion of the stones was observed in 32 cases（53.3%） of control group and 55 cases（91.7%） of experimental group.The difference in expulsion rate between two groups was statistically significant（P〈0.05）.Effective cases were 38 in control group and 57 in experimental group.The difference in effective rate between two groups was statistically significant（P〈0.05）.The mean expulsion time and renal colic recurred within 3 weeks were less in experimental group than in control group（P〈0.05）.No obvious side effects occurred.Conclusion：Naftopidil is safe and effective for the treatment of lower ureteral stones,and can significantly shorten expulsion time and reduce the rate of renal colic.
出处
《中国当代医药》
2010年第31期51-52,共2页
China Modern Medicine
