正畸牙移动对炎性大鼠牙周组织改建的实验研究

Role of orthodontic tooth movement in periodontal tissue remodeling in rats with periodontitis:An experimental study

目的:对比分析牙周炎牙移动和正常牙移动对牙周组织改建的影响。方法:72只Wistar大鼠随机平分为牙周炎牙移动及正常牙移动0d、1d、3d、7d、14d、21d组,共12组。近中移动各组大鼠上颌第一磨牙,分别测量各组大鼠牙齿移动距离并进行HE染色分析。结果:在既定时间内,牙周炎组大鼠牙移动距离大于正常组;与正常组比较牙周炎牙移动组压力侧破骨现象明显,张力侧成骨延缓。结论:进行正畸治疗一定要注意并维护牙周组织健康,对牙周炎正畸患者要进行彻底的牙周治疗和维护。

Objective：To compare and analyze the effect of the tooth movement in periodontitis and the normal tooth movement on the periodontal tissue remodeling.Methods：Seventy-two Wistar rats were randomly divided into normal tooth movement and periodontitis tooth movement with 0 day group,1 day group,3 day group ,7 day group,14 day group and 21 day group（a total of 12 groups）.The mesial movement of the maxillary first in each group was carried out and the distance of teeth movement was measured and the sections were detected by HE-stain.Results：In a given period of time,the distance of the tooth movement in periodontitis was longer than that in normal group;compared with normal tooth movement group,and the pressure side showed the clear osteoclastic phenomenon and the tension side showed the delayed bone formation.Conclusion：It is important to note and maintain periodontal health in orthodontic treatment,and a thorough periodontal treatment and maintenance are essential to periodontitis patients.