苯并寡聚乙二氧链螺旋体的合成

Synthesis of spiral compounds incoraporating 1,4-benzene and oligo(ethylene glycols)

以对甲氧基苯酚、对苄氧基苯酚、对苯二酚和四乙二醇二磺酸酯这些简单化合物为原料,通过磺酸酯与酚的亲核取代反应及苄基保护、钯碳氢化去保护策略制备得到了4种新颖的苯并寡聚乙二氧链螺旋体化合物.

4 novel spiral compounds incoraporating 1,4-benzene and oligo（ethylene glycols） were synthesized from 4-methoxyphenol,4-（benzyloxy） phenol,1,4-diphenol and tetraethyleneglycol ditosylate by nucleophilic substitution of tosylate and phenol,protection with benzyl group and deprotection of benzyl group with hydrogenation on Pd/C.