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右美托嘧啶用于硬膜外麻醉下妇科手术患者镇静的临床观察 被引量:24

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摘要 目的探讨右美托嘧啶用于硬膜外麻醉下妇科手术患者镇静的安全性和可行性。方法 100例硬膜外麻醉下择期行子宫和(或)卵巢切除患者随机分成右美托嘧啶组(D组)和对照组(C组)两组,应用Ramsay镇静评分和脑电双频谱指数等对右美托嘧啶在患者术中镇静效果进行观察。结果 D组患者在静脉注射右美托嘧啶后脑电双频谱指数显著低于对照组,Ramsay评分也相应升高(P<0.05),而C组则无明显变化;D组患者在术中各时间点心率显著低于C组,平均动脉压两组无明显差异;两组患者均无呼吸抑制情况的发生。结论右美托嘧啶用于硬膜外麻醉下妇科手术患者镇静是安全和可行的,可提供满意镇静且不抑制患者呼吸,BIS可以很好地反映其镇静深度。
出处 《广东医学》 CAS CSCD 北大核心 2010年第20期2710-2712,共3页 Guangdong Medical Journal
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