抗氧化中药治疗工业性氟病

Clinical Efficacy of Anti oxidation Preparation of Traditional Chinese Medicine in the Treatment of Industral Fluorosis

０例工业性氟病患者连续服用抗氧化中药（绞股蓝－丹参复方制剂）１年，尿氟排泄量逐月增加，于３个月达高峰，并维持于较高水平至服药结束，具有显著性差异（Ｐ＜０００５）；头发和指甲氟含量明显减少（Ｐ＜０００５）；超氧化物歧化酶（ＳＯＤ）活性增加（Ｐ＜００１）；丙二醛（ＭＤＡ）含量减少（Ｐ＜００５）。骨Ｘ线片显示部分骨密度减低，骨Ｘ线片好转率１３６４％。服药后患者感骨关节疼痛减轻。服药期间未发现不良反应。

Sixty cases of patients of industrial fluorosis were treated with anti-oxidation preparation of traditional Chinese medicine for one year.It is found that fluoride concentration in urine of the patients gradually increased, and reached a high peak from three-months of the treatment and remained until the treatment finished. There was specially significant difference between before and after the treatment (P<0 005),fluroide concentration in hair and nail of the patients marked decreased, superoxide dismutase(SOD)activity in red blood cell increased and malonaldehyde(MDA) concentration in blood plasma decreased. X-rays showed that density of bone decreased,pain in bone and joint of the patients eased after the treatment, side effect was not observed during study.