台州地区肺炎支原体肺炎患儿诱导痰细菌培养及药敏分析

Mycoplasma pneumonia induced sputum bacterial culture and drug susceptibility in Taizhou region

目的了解肺炎支原体肺炎患儿合并细菌感染的致病菌及耐药情况。方法对408例确诊为肺炎支原体肺炎的患儿痰标本进行培养及药敏试验。结果 408例标本检出致病菌203株,其中革兰阴性菌154株(75.9%)、革兰阳性菌28株(13.8%)、真菌19株(9.4%)。主要致病菌依次为肺炎克雷伯菌75株(36.9%)、大肠埃希菌53株(26.1%)、金黄色葡萄球菌18株(8.9%)、产气肠杆菌10株(4.9%)、铜绿假单胞菌8株(4.0%)。结论肺炎支原体肺炎患儿合并细菌感染的病原菌以革兰阴性菌为主,不同的细菌对常用的抗生素存在不同程度的耐药,临床上应针对非典型病原体使用抗生素的同时合理使用其它抗生素。

OBJECTIVE To know about pathogenic bacteria and drug resistance in mycoplasma pneumonia complicated with bacterial.METHODS Sputum culture and drug susceptibility testing were done in 408 patients diagnosed as Mycoplasma pneumonia.RESULTS 203 samples in 408 cases were detected with pathogens,including gram-negative bacteria 154（75.9%）,gram-positive bacteria 28（13.8%）,fungal 19（9.4%）.Major pathogens were in turn Klebsiella pneumoniae 75（36.9%）,Escherichia coli 53（26.1%）,Staphylococcus aureus 18（8.9%）,Enterobacter aerogenes 10（4.9%）,8 strains of Pseudomonas aeruginosa（4.0%）.CONCLUSION Mycoplasma pneumoniae pneumonia in children with bacterial infections Gram-negative bacteria,different bacteria to commonly used antibiotics in different degrees of resistance,clinical atypical pathogens should be used for the rational use of antibiotics,while other antibiotics.