褶合光谱法测定复方氧氟沙星滴耳液含量

Determination of compound ofloxacin ear drops by convolution spectrometry method

目的：不经分离直接测定氧氟沙星和氢化可的松的含量。方法：采用褶合光谱法。结果：二组分的回收率和ＲＳＤ分别为１００２４％，０６８％；１０００９％，０６１％。结论：本法结果可靠、准确，适于该耳液的含量测定。

OBJECTIVE: To determine ofloxacin and hydroctisone in compound ofloxacin ear drops without separation. METHODS: The convolution spectrometry method was used. RESULTS: The average recovery and RSD of ofloxacin and hydrocortisone acetate were as 100.24%,0.68%;100.09%,0.61%. CONCLUSION: The method is convient,accuracy and suitable for the determination of ear drops.