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快速非整倍体胎儿产前诊断技术

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摘要 染色体病是因染色体数目、结构畸变造成遗传物质得失所引起的遗传性疾病，目前的医疗水平难以治疗或无法治疗，因此产前诊断尤为重要。我国大规模开展的产前诊断手段主要是细胞遗传学染色体核型分析，所培养的羊水细胞和绒毛细胞核型分析的精确度分别为99．4％～99．8％和97．5％～99．6％．
作者 禹虹 边旭明
机构地区 中国医学科学院北京协和医学院北京协和医院妇产科
出处 《协和医学杂志》 2010年第1期98-102,共5页 Medical Journal of Peking Union Medical College Hospital
关键词 产前诊断 快速非整倍体检测技术 荧光原位杂交技术 荧光定量聚合酶链反应
分类号 R715.5 [医药卫生—妇产科学]
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参考文献24

  • 1徐爱群,边旭明.荧光原位杂交技术用于快速产前诊断临床评价[J].国际妇产科学杂志,2009,36(3):172-177. 被引量：6
  • 2王晨虹,周璐,李胜利,袁晖.荧光原位杂交与核型分析技术产前诊断非整倍体的对比研究[J].现代妇产科进展,2009,18(3):201-204. 被引量：7
  • 3鲍如蓉,朱宝生,苏洁,唐新华.唐氏综合征快速产前诊断方法的研究[J].黔南民族医专学报,2009,22(1):18-22. 被引量：1
  • 4周大文,许淼,颜景斌,任兆瑞.应用MLPA-微阵列技术分析基因组内拷贝数变异的初步探讨[J].现代诊断与治疗,2008,19(2):98-102. 被引量：5
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二级参考文献45

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协和医学杂志
2010年 第1期

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