急性外周动脉栓塞介入溶栓治疗分析

The analysis of interventional thrombolysis for Acute Peripheral Arterial Embolism

目的评价介入性动脉内置管于血栓处,局部持续泵入尿激酶治疗急性动脉栓塞的临床效果。方法 18例急性外周动脉栓塞病人,采用Seldinger法经健侧股动脉穿刺引管行动脉造影,找出动脉血栓部位后,将导管导丝插入,把溶栓导管引入血栓中,先给予高浓度尿激酶脉冲灌注,后持续泵入尿激酶,定期造影复查,根据血栓溶解情况及时灵活调整导管位置及尿激酶用量。结果急性动脉栓塞病人治愈率为83.3%,无出血等严并发症。结论经导管动脉内血栓局部溶栓及持续泵入尿激酶治疗急性动脉栓塞效果显著。

Objective To evaluate the therapeutic efficacy of arterial thrombolysis with urokinase in the treatment of acute artery embolism.Methods Eighteen cases of acute peripheral arterial embolism were used the Seldinger method to puncture femoral artery.After finding the parts of arterial thrombosis,a catheter was inserted into thrombus to give the high concentration of urokinase pulse infusion,then continuous infusion of urokinase.Check the angiography periodically,and according to thrombolytic situation adjust the location of catheter and the dose of urokinase timely.Result The cure rate of the patients treated was 83.3%,no severe complication,such as hemorrhage,was encountered.Conclusion Regional thrombolysisusing intraarterial continuous infusion for acute artery embolism is effective.