N-磷酰化丙氨酸分子内混酐假旋转异构体的MNDO研究

An MNDO Research on Pseudo-rotation isomers of Intramolecular Mixed Anhydride Formed from N-diisopropylphosphoryl-alanine

用ＭＮＤＯ半经验分子轨道计算方法对Ｎ－磷酰丙氨酸生成的五配位磷中间体的假旋 转异构体的结构和性质进行了研究。结果表明这些异构体是高活性的，并且具有不同的反应 性质，因此他们可能成为具有多重反应性的合成子．

By means of MNDO MO calulations,the structures and properties of pseudo-rotation isomers of an pentacoordinate phosphorus intermediate formed from N-phosphoryl-a-alanine were studied.As it truned out that the isomers are hihgly active and have various reactiveties,therefore they may become synthons with multi-activity.