摘要
目的:测定消糜止痒栓中苦参碱、氧化苦参碱的含量。方法:采用高效液相色谱法(HPLC法)。色谱柱为C18柱,以甲醇-乙腈-pH6.8磷酸盐缓冲液(8:8:84)为流动相,检测波长为220 nm。结果:苦参碱进样量在0.104～1.04 μg、氧化苦参碱进样量在0.24～2.40μg范围内与峰面积积分值呈良好线性关系。结论:HPLC法快速、准确,可用于该制剂的质量控制。
Objective： To determine the contents of Matrine and Oxymatrine in Xiaomi Zhiyang Suppository. Methods： HPLC method was adopt- ed and a C18 columnwas used. The mobile phase was methanol- acetonitrile- phosphate buffer solution（pH =6.8） （8：8：84）.The detection wave- length was at 220 nm. Results： The linear ranges were 0.104- 1.04 μg for Matrine,0.24 - 2.40 μg for Oxymatrine, respectively.Conclusion： The methods is quick and accurate, can be used for quality control of Xiaomi Zhiyang Suppository.
出处
《内蒙古中医药》
2010年第19期91-92,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
