极低出生体重儿及极早早产儿1年随访

One Year Follow-up of Very Low Birthweight Infant and Extremely Preterm Infant

目的评估极低出生体重儿和极早早产儿随访到1岁时的体格发育状况、呼吸道感染频率及就诊频率等情况。方法将2008年5月至2009年5月四川大学华西第二医院新生儿科收治并存活出院的孕周小于32周或产重小于1500g的72例新生活产婴儿分为3组:第一组26例,孕周<32周而产重≥1500g;第二组18例,孕周≥32周而产重<1500g;第三组28例,孕周<32周且产重<1500g。于校正胎龄1岁时收集生长状况、呼吸道感染频率及就诊次数等信息。结果出院后随访到1岁时,第三组体重、头围的落后率高于第一组,身长的落后率高于第一组和第二组;第三组的中位呼吸道感染频率(15.5)较第一组(12.5)和第二组(8.5)高,第三组中位就诊次数(27.5)比第一组(17.5)和第二组(15.5)高。结论本研究结果提示,校正胎龄1岁时同是极低出生体重儿和极小胎龄早产儿的随访情况较仅为极低出生体重或极小胎龄的患儿要差,因此,胎龄和产重在评估早产儿预后方面同样重要。

Objective To assess the growth station,the upper respiratory infection frequency and consultation fre-quency of the geographically de ned high risk neonatal population at 1-year-old based on both birthweight and gestation-al age.Methods All infants admitted in our hospital from May in 2008 to May in 2009 were divided into three groups according to gestational age and birth weight,that were,group 1： born 32 completed gestational weeks and weighing ≥1？500 g;group 2： born after 32 completed gestational weeks and weighing 1？500 g;and group 3： born 32 completed gestational weeks and weighing 1？500 g.Information at 12 months corrected age about growth,the upper respiratory in-fection frequency and consultation frequency was collected.Results The growth rate of weight and head circumference in group 3 were lower than that in group 1,and the length growth rate was lower than that in group 1 and group 2.Infants in group 3 su ered from more airway infections（median： 15.5） than in group 1（12.5） and group 2（8.5）.Infants in group 3 needed more medical consultations（median： 27.5） than those in group 1（17.5） and group 2（15.5）.Conclusions This study gives estimates for growth outcome,airway infection and consultation frequency at 12 months corrected age for very low birthweight infants（1？500 g） and for very preterm infants（32 completed gestational weeks）.Gestational age and birth weight are the same important for predicting infants’ outcome and should therefore be integrated into clinical statistics.