中西药联合治疗糖尿病肾病的临床研究

目的:糖尿病肾病之中西药联合治疗研究。方法:单纯西药治疗和中西药联合治疗糖尿病肾病的疗效比较。结果:治疗后两组24小时UMA,HbA1c均较治疗前有明显下降(P<0.01),且治疗组的下降幅度均大于对照组(P<0.05);治疗后两组SBP、DBP均较治疗前有明显下降(P<0.01),但两组间差异无统计学意义;两组治疗前后BUN、Cr变化均不明显。结论:中西药联合治疗早期糖尿病肾病,在控制血糖血压的同时还显著减少了24小时尿微量白蛋白,效果优于单用西药治疗,且无明显不良反应,值得临床推广使用。

Objective：To Research The Diabetic Nephropathy Combined Treatment with Chinese Medicine And Western Medicine. Methods：To Compare the Diabetic Nephropathy Treatment effects between Only western medicine and Chinese Medicine Combined with Western Medicine. Results： obviously decreasing in 24hUMA and HbAlc of the two groups after treatment（ P 〈 0. 01 ）. The decrease in the treatment group is more than which in the control group （ P 〈 0. 05 ）. The SBP, DBP of both groups have obviously decreased after treatment （ P 〈 0. 01 ）. the difference between the two groups has no statistical significance. The BUN and CR have no marked changes after treatment. Conclusion： The combined treatment with chinese medicine and western medicine for the early stage of diabetic nephropathy can decrease the 24hUMA as well as control glycemic and blood pressure, which effect is better than in only use western medicine,and which has no observed adverse effect. It is deserved to been clinically spread and applied.