ALT/ALP比值在黄疸鉴别诊断中的应用

Application of ALT/ALP in Differential Diagnosis of Jaundice

目的:研究ALT/ALP比值(R值)对肝细胞性黄疸与胆汁淤积性黄疸的鉴别诊断价值,并比较R值与传统的D/T(DBIL/TBIL)值两者的诊断灵敏度。方法:回顾性分析2004年1月至2006年12月我科收治的显性黄疸患者336例的临床资料,计算R值与D/T值。结果:肝细胞性黄疸的诊断阳性率R值为34.9%,D/T值为16.1%,R>D/T(P<0.05),对胆汁淤积性黄疸的诊断阳性率D/T值为93.0%,R值为75.4%,D/T>R(P<0.05)。结论:对肝细胞性黄疸的诊断阳性率,R值高于D/T,而对胆汁淤积性黄疸的诊断阳性率D/T优于R值。

Objective： To study the diagnostic value of ALT/ALP （R value） with regard to differential diagnosis between hepatocellular jaundice and eholestatic jaundice, and to compare diagnostic sensibility of R value to D/T （DBIL/TBIL）value. Methods： The clinical data of 336 patients with clinical jaundice from Jan.2004 to Dec.2006 were analyzed retrospectively. The R value and D/T value were calculated. Results： Diagnosis rate of R value and D/T value were 34.9% and 16.1% in cases of hepatocellular jaundice, R〉D/T （P〈0.05）. Diagnosis rate of D/T value and R value were 93.0% and 75.4%in cases of cholestatic jaundice, D/T〉R （P〈0.05）. Conclusions： Diagnosis rate of R value is higher than that of D/T value in hepatoeellular jaundice, diagnosis rate of D/T value is higher than that of R value in eholestatic jaundice.