儿童炎症性肠病28例临床和内镜特点分析

Analysis of the Clinical and Endoscopic Features of 28 Pediatric Inflammatory Bowel Diseases

目的:研究儿童炎症性肠病(IBD)的临床和内镜特点。方法:以病例对照的方法分析28例儿童IBD的临床资料。结果:儿童IBD以腹痛、腹泻、便血、贫血、低蛋白血症、ESR与CRP升高为主要表现;溃疡性结肠炎(UC)的病变以广泛或全结肠型和内镜下表现为Ⅲ和Ⅳ级者明显多于成人IBD;克罗恩病(CD)内镜表现为全结肠型并有"铺路石"样改变,而典型的裂隙状或纵行溃疡少见。结论:儿童IBD的临床与内镜具有一定的特点。

Objective： To investigate the clinical and endoscopic features of pediatric inflammatory bowel disease （IBD）. Method： The clinical data of 28 pediatric IBD were analyzed by case-control study. Results： The main features of pediatric IBD were abdominal pain, diarrhea, bleeding stool, anemia, hypoalbuminemia, elevation of ESR and CRP. There were more common of the extensive or pancolitis and the grade BI and IV under endoscopiy in pediatric ulcerative colitis （UC） than in adult UC. The common endoscopic features of pediatric Crohn＇s disease （CD） were pancolitis and cobblestoning, but the fewer were aphthous or linear ulcers. Conclusion： There are special clinical and endoscopic features of pediatric IBD.