2型糖尿病伴胸痛的患者冠状动脉造影分析

Coronary angiographic analysis in type 2 diabetic patients with chest pain

目的观察2型糖尿病(T2DM)伴胸痛的患者冠心病(CAD)的疾病特点。方法以胸痛需行冠状动脉造影患者836例为研究对象,回顾性观察T2DM胸痛的患者CAD阳性率及CAD特点。结果 T2DM组140例,非T2DM患者(NT2DM组)696例。T2DM组冠心病阳性率明显高于NT2DM组(P<0.01)。T2DM组单支病变比NT2DM组明显少(P<0.01);双支病变比NT2DM组明显多(P<0.01);三支病变比NT2DM组明显多(P<0.01)。冠状动脉病变分布情况:左前降支病变T2DM组和NT2DM组无明显差别;右冠状动脉病变两组无明显差别;左回旋支病变两组无明显差别;左主干病变两组无明显差别。结论 T2DM伴胸痛的患者CAD发生率高,且双支病变和三支病变多。

Objective To observe the characteristics of coronary artery disease（CAD） in type 2 diabetic （T2DM） patients with chest pain. Methods A total of 836 patients were observed. Results In 836 cases with chest pain undergoing coronary angiography, 140 cases （16.7 %）with T2DM and 696 cases （83.3%） without T2DM （N T2DM） were found. T2DM group versus non-T2DM group showed a higher prevalences of coronary artery disease （71.4% vs 45.4%）, two branches of CAD（37% vs 29%）, three branches of CAD（40% vs 9%）,and a lower prevalence of single branch of CAD（20% vs 46%）（all P〈 0.05）. And non-T2DM group versus T2DM group showed a similar distribution of damaged CAD branches in left anterior descending artery （40. 7% vs 40.6%） ,left circumflex artery（24. 6% vs 23. 8%）, left main coronary artery（3. 5% vs 1.4%） and right coronary artery （31.2% vs 34. 2%） （all P〉0. 05）. Conclusions CAD incidence of type 2 diabetec patients with chest pain is higher than in non-diabetic patients with chest pain. The prevalence of two branches and three branches of lesions is higher in T2DM group than in non-T2DM group.