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阿司匹林对老年高血压患者血尿酸的影响及其预防 被引量:3

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摘要 目的探讨长期服用小剂量阿司匹林对老年高血压患者血尿酸的影响及别嘌醇的预防作用。方法用随机方法将老年轻、中度高血压患者102例分成治疗组和对照组,两组均采用氨氯地平和/或贝那普利降压治疗,治疗组加用肠溶阿司匹林100mg/d,半年后观察两组患者的血压、心率、血尿酸变化,此后,治疗组再加用别嘌醇100mg,3次/d,半年后再次观察上述指标。结果治疗组应用阿司匹林半年后,血尿酸水平较治疗前及对照组明显升高(P<0.05),加用别嘌醇治疗半年后血尿酸水平明显降低,且两组间无明显差异(P>0.05)。两组患者的血压、心率及其他生化指标始终无明显变化。结论长期服用小剂量阿司匹林可引起老年高血压患者的血尿酸增高,联用别嘌醇可起预防作用。
出处 《齐齐哈尔医学院学报》 2010年第19期3071-3072,共2页 Journal of Qiqihar Medical University
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