摘要
目的:研究黄粉虫蛋白对小鼠免疫功能的影响。方法:将黄粉虫蛋白分为高、中、低剂量组,分别为1.25,2.5,5 g·kg-1·d-1喂饲小鼠20 d,观察对小鼠免疫器官指数、碳廓清能力、迟发型变态反应(DTH)、溶血素抗体4个检测项目的影响。结果:黄粉虫蛋白明显增加小鼠脾和胸腺脏器指数,增加小鼠足跖肿胀度,促进小鼠巨噬细胞的吞噬活力和溶血素抗体生成。结论:黄粉虫蛋白具有增加小鼠免疫器官重量、增强小鼠细胞免疫、激活和增强单核-巨噬细胞功能、刺激B淋巴细胞产生抗体的作用。
Objective: To study the effects of Tenebrio molitor proteins on immune function in mice.Method: Effects of T.molitor proteins on immune organs' indexes,carbon clearance ability,delayed type hypersensitivity(DTH),hemolysin antibody were investigated in mice.Result: T.molitor proteins could significantly increase weight of immune organs and swelling in foot sole of mice.T.molitor proteins could enhance macrophage phagocytic activity and production of hemolysin antibody.Conclusion:T.molitor proteins can enhance the immune function in mice significantly.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第15期87-89,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(30872367)
省教育厅重点项目(KJ2007A033)
关键词
黄粉虫蛋白
免疫功能
迟发型变态反应
巨噬细胞
Tenebrio molitor proteins(TS); immune function; delayed type hypersensitivity; macrophages;