926株病原菌分布及耐药性分析

Bacteria Distribution of 926 Strains and Drug Resistance Analysis

目的了解病原菌分布特点及耐药现状,为临床抗菌药物的应用提供依据。方法对医院分离出的926株病原菌的分布情况进行回顾分析,同时统计其耐药率。结果从2007年1月-2009年10月,共收到各种送检标本2183份,检出病原菌926株,检出阳性率为42.42%,其中革兰阴性杆菌563株,占60.80%,革兰阳性球菌236株,占25.49%,真菌127株,占13.71%;真菌和革兰阴性杆菌的感染呈逐年上升趋势;易感人群多为慢性病患者或老年人群,感染部位以呼吸道为主,病原菌对多种抗菌药物耐药并呈逐年上升趋势。结论病原菌的感染及耐药现状不容乐观,医院应加强病原学监测,及时了解病原学动态,加强合理使用抗菌药物管理,最大程度减少耐药菌株的产生。

OBJECTIVE To analyze the characteristics of bacteria distribution and resistance to antibiotics, to provide the basis for clinical application. METHODS The distribution of pathogenic bacteria of 926 strains isolated were statistically analyzed, and their resistance was reviewed. RESULTS From Jan 2007 to Oct 2009, 2183 various specimens were collected, from them the 926 pathogen strains were isolated and the detection rate was 42. 42%. The G- occupied 60. 800/oo （563 strains）, G＋ 25. 49% （236 strains） and the fungi 13. 71% （127 strains）. The fungi and G- were increasing year by year. The for patients were mostly with chronic diseases and the elderly the main infection site was the respiratory tract, and the antibiotic resistance was increasing year by year. CONCLUSIONS The infection and drug-resistance status are unfavorable. Hospital should strengthen and timely monitor the etiology, and minimize drug-resistant strains in order to reasonable use of antibiotics.