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结核分枝杆菌耐多药现状调查分析 被引量:5

Present Situation of Multi-drug Resistant Mycobacterium tuberculosis
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摘要 目的了解结核分枝杆菌的医院感染和耐多药现状,以采取有效措施控制医院感染,同时为临床合理用药提供科学依据。方法对2008年1月-2009年12月,医院1460例肺结核菌阳性患者痰标本分离的结核分枝杆菌培养与药敏试验的结果进行回顾性分析。结果 1460株结核分枝杆菌株中耐多药占40.68%;多耐药的肺结核菌株占23.58%;单耐药占35.74%。结论各级结核病医院必须重视结核分枝杆菌的耐药监测,预防耐多药菌株的传播与流行。 OBJECTIVE To understand the status of Mycobacteriurn tuberculosis and multi-drugresistant nosoeomial infection, to take effective measures to control nosocomial infection, as well as to provide the scientific basis for clinical rational drug use. METHODS The sputum M. tuberculosis culture and drug susceptibility test results of 1460 cases of tuberculosis hospital patients admitted from Jan 2008 to Dec 2009 were analyzed retrospectively. RESULTS M. tuberculosis multidrug-resistant strains accounted for 14.66%. Among the 1460 strains of tested M. tuberculosis, multi-drug resistant strains of tuberculosis accounted for 23.58%, single drug resistant strains aecounted for 35.74%. CONCLUSION Tuberculosis hospitals at all levels should attach importance to the drug resistance of M. tuberculosis and prevention of the spread of multi-drug resistant strains and epidemics.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2010年第22期3626-3627,共2页 Chinese Journal of Nosocomiology
基金 国家十一五重大科技专项课题(2008ZX10005-010)
关键词 结核分枝杆菌 耐药性 医院感染 监测 Mycobacteriurn tuberculosis Multi-drug resistance Nosocomial infection Monitor
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