子宫颈蓝痣47例临床病理分析

A Clinicopathologic Analysis of 47 Cases with Uterine Cervix Blue Nevus

目的探讨子宫颈蓝痣的临床病理特点及其发生发展。方法对４７例宫颈蓝痣进行常规病理检查，部分病例加Ｍａｓｏｎ－Ｆｏｎｔａｎａ及Ｐｅｒｌｓ染色。结果宫颈蓝痣的发病率为５３％，病灶均位于颈管内，宫颈上段是最多见的部位。蓝痣细胞胞浆内有色素颗粒，Ｍａｓｏｎ－Ｆｏｎｔａｎａ染色证实为黑色素。结论宫颈蓝痣并非罕见，其来源可能与苗勒氏管尾端发育阶段有关，应与宫颈恶黑鉴别。

Objective\ To investigate the clinicopathologic features of uterine cervix blue nevus and discuss their origin and development.Methods\ 47 cases of blue nevus were observed through routine pathologic examination,some of them with Masson-Fontana and Perls staining.Results\ The incidence of uterine cervix blue nevus was 5 3%,all of them were located within cervical canal.The nevus cells contain pigment.The Masson-Fontana staining confirmed that they are melanin.Conclusions\ Blue nevus were not very rare in cervix,its origin was not clear,but may be associated with the early stage of the mullerian duct end development.