氢化可的松和哌替啶对剖宫产蛛网膜下腔麻醉后寒战反应的疗效

Effects of treatment with ethidine and hydrocortisone on post-spinal anaesthesia shivering in cesarean section

目的:评价氢化可的松和哌替啶对椎管内麻醉后寒战的治疗作用。方法:选择剖宫产初产妇术后,Wrench分级2级及其2级以上患者80例,分为氢化可的松2.0mg/kg组、哌替啶0.05mg/kg组和生理盐水10ml组。术中监测心电图(ECG)、脉搏氧饱和度(SpO2)、血压(BP)、心率(HR)、肛温(T)。记录各组寒战发生时(T1),寒战后10min(T2)、30min(T3)、60min(T4)体温,对以上4个时间点的寒战进行评分,并观察不良反应的发生情况。结果:3组患者术后随访发现,哌替啶组恶心、呕吐发生率较氢化可的松高(P<0.05)。哌替啶组和氢化可的松组患者麻醉后寒战缓解迅速,寒战持续时间较短,症状较轻。结论:氢化可的松治疗麻醉后寒战较少引起恶心、呕吐等副作用,可用于剖宫产麻醉后寒战的治疗。

Objective：Evaluating the effects of treatme nt with pethidine and hydrocortisone on post-spinal anaesthesia hivering.Methods：Eighty patients with cesarean section（Wrench Ⅱ～Ⅳ） were divided into three group：pethidine（0.05 mg/kg） group,hydrocortisone（2.0 mg/kg） group and normal saline group.Signs and parameters such as body temperature,blood pressure were monitored during the operation.Checking in body temperature 0,10,30 and 60 min after shivering,evaluating the side effects of shivering such as nausea and vomiting.Results：The incidence of nausea and vomiting was much lower in hydrocortisone group than in pethidine and saline group.Pethidine group and the hydrocortisone group quickly alleviate shivering after anesthesia,short duration of chills.Conclusions：Treatments with hydrocortisone were effective in treating post-anesthesia shivering.