冠心病患者一氧化氮含量的变化

Clinical study of changes of plasma nitric oxide levels in patients with coronary heart disease

目的：探讨一氧化氮（ＮＯ）与冠心病的关系。方法：测定３６例冠心病患者血清中ＮＯ，超氧化物岐化酶（ＳＯＤ）和丙二醛（ＭＤＡ）含量，２８例健康人作为正常对照。结果：与正常对照组比较，冠心病者ＮＯ、ＳＯＤ含量显著降低（Ｐ＜０．０５），ＭＤＡ含量显著增高（Ｐ＜０．０１）。结论：血清ＮＯ、ＳＯＤ、ＭＤＡ含量与冠心病发生、发展有关。

Objective:To study the relationship between nitric oxide and coronary heart desease.Methods:Test of NO,SOD and MDA in blood plasma was performed for 36 cases of coronary heart desease.The control group included 28 healthy persons.Results:Compared with the control group,NO and MDA in plasma for coronary heart desaase are clearly decreased( P <0.05),while MDA is obviously increased( P <0.01).Conclusion:NO, SOD and MDA are likely associated with causes of coronary heart disease.