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幽门螺旋菌在各期胃癌中的检出率与分布 被引量:1

Changes on positive rate and distribution of helicobacter pylori during progression of gastric cancer
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摘要 对7例早期胃癌和42例中晚期胃癌活检组织,作HE染色及石碳酸碱性品红法染色显示幽门螺旋菌(HP)。结果表明:42例中晚期胃癌患者HP阳性率为238%,7例早期胃癌患者HP阳性率为571%,两者差异有高度显著性(P<0.01)。在HP阳性的患者,HP并不分布于癌变组织,而是分布于癌旁“正常”组织,在中晚期胃癌的HP分布较早期胃癌更稀疏。提示HP与胃癌的进展关系不大。 We observed changes on the positive rate and the distribution of helicobacter pylori (HP) in 7 case during early stage of gastric cancer and in 42 cases during middle late stage of gastric cancer. The results showed that ①the positive rate during early stage of gastric cancer was 57.1%, the positive rate during middle rate stage of gastric cancer was 23.8%, ②HP was not found within the gastric cancer lesions, ③for HP positive cases, HP distribution during early stage of gastric cancer was more sparse than during middle late stage of gastric cancer. These results suggested that HP can hardly live within the gastric cancer tissue, so the progression of gastric cancer is probably independent of HP. It may be a question that HP eradication can prevent later development of gastric cancer.
出处 《湖南医科大学学报》 CSCD 1999年第2期161-163,共3页 Bulletin of Hunan Medical University
关键词 幽门螺旋菌 组织活检 胃肿瘤 检出率 helicobacter pylori gastric cancer biopsy tissue
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