不同血液透析年限病人桡尺骨骨密度的研究

Investigation of the bone mineral density in hemodialysis patients for different terms

为了解不同血液透析年限病人的骨密度情况，按不同透析时间，将５０例长期血液透析的慢性肾功能衰竭病人分为三组，Ⅰ组血透＜５年，Ⅱ组血透５～１０年，Ⅲ组血透＞１０年。采用双能Ｘ线骨密度测定法检测三组患者的桡尺骨骨密度，同时检测其血清钙、磷、铝和甲状旁腺激素（ＰＴＨ）。结果显示，不同透析时间患者的骨密度及ＰＴＨ三组间无显著差别。提示长期血透病人的骨密度不受透析时间的影响。

The investigate the change of bone mineral density(BMD) in hemodialysis patients for different terms of hemodialysis, 50 patients were divided into three groups according to the duration of hemodialysis. Group Ⅰ was <5 years. Group Ⅱ was 5～10 years, and Group Ⅲ >10 years. The BMD of the patients were assayed by using dual energy X ray bone absorptiometer. Serum calcium, phosphorus, aluminium, and intact parathyroid hormone(iPTH) were detected at the same time. The mean BMD and serum iPTH were 0.624±0.180g·cm -2 and 9.67±9.46ng·cm -1 in Group Ⅰ, 0.573±0.160g·ml -2 and 10.16±28.05ng·ml -1 in Group Ⅱ, and 0.513±0.117g·cm -2 and 10.75±24.94ng·ml -1 in Group Ⅲ, respectively. There was no statistical significance in BMD ( P >0.05) and iPTH( P >0.05) among the above groups. The BMD of hemodialysis patients is not affected by different terms of hemodialysis.