杜仲素抗氧化活性研究

Antioxidant Effect of Eucommin

以VC为阳性对照,对杜仲素和高纯绿原酸清除羟自由基(·OH)、超氧阴离子自由基(O·)及1,1-二苯基-2-苦苯肼自由基(DPPH自由基)活性进行研究,并通过计算清除率比较清除各种自由基活性的效果。结果表明:杜仲素在不同自由基体系中抗氧化活性不同,清除自由基能力为O·>DPPH自由基>·OH,对3种自由基的最大清除率依次为95.85%、75.31%和31.10%。因此,杜仲素具有较强的抗氧化作用。

To provide theoretical evidences for developing novel natural antioxidants,eucommin and high-purity chlorogenic acid were assessed for their antioxidant effects by hydroxyl,superoxide anion and DPPH free radical assays with vitamin C as a positive control. Curves of free radical scavenging ratio versus concentration were plotted for each of these three compounds. As a result,eucommin had different scavenging effects against different radicals and the best ability to scavenge superoxide anion radicals,followed by DPPH and hydroxyl radicals,with corresponding maximum scavenging ratios of 95.85%,75.31% and 31.10%. Therefore,eucommin is a potential strong antioxidant.